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Obtained data showed, that application of SHBG not only reduces the expression of pro-inflammatory cytokines but also promotes the activity of anti-inflammatory ones including IL-4 , IL-10 and IL-13

Biotin is a water soluble vitamin, known as B7 or Vitamin H, and can improve the basic protein that makes up hair, skin and nails

So theres definitely some very interesting preliminary evidence

J Physiol Paris 93:479485 Sikiric P, Seiwerth S, Brcic L, Blagaic AB, Zoricic I, Sever M, Klicek R, Radic B, Keller N, Sipos K et al (2006) Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)

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These biological properties explain why GHK-Cu is central to many advanced regenerative and aesthetic formulations